Optical methods of probing sub-nm vibrations and nanoarchitecture in biological tissues

Date: 
Monday, February 20, 2012 -
4:00pm to 5:00pm
Speaker: 
Stephen Jacques
Speaker's Institution: 
Oregon Health and Science University

Optical methods can interrogate biological tissues to measure sub-nm vibrations and nanoarchitecture. The wavelength dependence of light scattering can characterize the nanoarchitecture of cells and tissues. Reflectance confocal microscopy can characterize the anisotropy of scattering, which is sensitive to changes in nanoscale structure of biomaterials.  Interferometry can characterize the granularity of the nucleus.  Interferometry can measure the sub-nm vibrations of the cochlear membrane of the inner ear in vivo. This talk will present our current work on such optical techniques.